Duncanopsammia axifuga is a common addition to many Australian reef tanks. Usually found in deeper water near sandy substrate, Duncanopsammia axifuga is very adaptable to lighting conditions. Coloration can vary from gray-pink to light green on the tentacles, a pink to intense blue-green on the oral disc and brown to bright green on the corallites. The size of polyps (including tentacles) can be up to approximately 4.5 cm across, while the corallites are approximately 1 cm to 1.5 cm across.

Duncanopsammia axifuga is a relatively unaggressive coral, incapable of producing sweeper tentacles, and generally comes out underneath when competing with other stony corals. It is best left with plenty of space to grow, as well as relatively unaggressive neighbours such as Blastomussa sp.